C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2749200
The present invention provides human anti-IL-6 antibodies with extended in vivo half-life. The invention further relates to pharmaceutical compositions, therapeutic compositions, and methods using therapeutic antibodies that bind to IL-6 and that has an extended in vivo half-life for the treatment and prevention of IL- 6 mediated diseases and disorders, such as, but not limited to, inflammatory diseases and disorders, autoimmune diseases and disorders and tumors.
L'invention porte sur des anticorps humains anti-IL-6 à demi-vie prolongée in vivo. L'invention porte également sur des préparations pharmaceutiques, des compositions thérapeutiques et des méthodes utilisant des anticorps thérapeutiques se fixant à l'IL-6 et à durée de vie prolongée in vivo pour la prévention et le traitement de maladies et de troubles médiés par l'IL-6, tels que non exclusivement des maladies et troubles inflammatoires, des maladies et troubles autoimmuns et des tumeurs.
Bowen Michael
Coyle Anthony
Dall'acqua William
Jallal Bahija
Kiener Peter
Medimmune Llc
Smart & Biggar
LandOfFree
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