C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01)
Patent
CA 2595276
The invention relates to fully human antibodies, and fragments thereof, that bind to human interferon gamma (hlFN.gamma.), thereby modulating the interaction between IFN.gamma. and its receptor, IFN.gamma.-R, and/or modulating the biological activities of IFN.gamma.. The invention also relates to the use of such anti-IFN.gamma. antibodies in the prevention or treatment of immune- related disorders and in the amelioration of a symptom associated with an immune-related disorder.
La présente invention a trait à des anticorps pleinement humains, et à des fragments de ceux-ci, de liaison à l'interféron gamma humain (hlFN?), permettant ainsi une modulation de l'interaction entre l'IFN? et son récepteur, l'IFN?-R, et/ou la modulation des activités biologiques de l'IFN?. L'invention a également trait à l'utilisation de tels anticorps anti-IFN? dans la prévention ou le traitement de troubles liés au système immunitaire et dans l'amélioration d'un symptôme associé à un trouble lié au système immunitaire.
Elson Greg
Ferlin Walter
Fischer Nicolas
Leger Olivier
Novimmune S.a.
Ridout & Maybee Llp
LandOfFree
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