Human anti-rh(d) monoclonal antibodies

Details Human anti-rh(d) monoclonal antibodies Human anti-rh(d) monoclonal antibodies

G - Physics

01

N

167/139, 195/1.1

G01N 33/80 (2006.01) A61K 39/395 (2006.01) C07K 16/34 (2006.01) C12N 5/00 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1303534

- 26 - ABSTRACT Human Anti-Rh(D) Monoclonal Antibodies The present invention provides human monoclonal antibodies having the following essential characteristics: (a) exhibiting activity against Rh(D) antigen, but not C, c, E or e antigens of the Rh blood group system; (b) being IgG3 proteins; (c) having kappa light chains; (d) being of the allotype G3m(21); (e) exhibiting activity against Du cells by an indirect antiglobulin test; (f) exhibiting activity against DIV, DV and DVII variant antigens; and (g) being inactive against DVI or DB variant antigens, which may be employed for Rh-typing of red blood cells and passive immunisation to prevent haemolytic disease of the newborn. Such a monoclonal antibody is exemplified by the monoclonal antibody of cell line ECACC 87091606 deposited at the European Collection of Animal Cell Cultures, Porton Down, U.K. on 16th September 1987.

577600

Affiliated with

Also associated with

Rating

Human anti-rh(d) monoclonal antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human anti-rh(d) monoclonal antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human anti-rh(d) monoclonal antibodies will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1305598