C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12N 5/078 (2010.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) C40B 40/02 (2006.01) C40B 40/08 (2006.01) C40B 40/10 (2006.01) C40B 50/06 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2385709
The invention uses the power of display selection methods to screen libraries of human immunoglobulin genes from nonhuman transgenic animals expressing human immunoglobulins. Such screening produces unlimited numbers of high affinity human antibodies to any target of interest.
L'invention met en application des procédés de sélection d'affichage servant à cribler des banques de gènes humains d'immunoglobuline provenant d'animaux transgéniques non humains exprimant des immunoglobulines humaines. Ce criblage permet d'obtenir des nombres illimités d'anticorps humains d'affinité élevée contre toute cible recherchée.
Buechler Joe
Gray Jeff
Lonberg Nils
Valkirs Gunars
Barrigar Intellectual Property Law
Biosite Diagnostics Inc.
Biosite Incorporated
Inc. Genpharm International A. Subsidiary Of Medarex
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