C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12P 19/34 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2406342
As novel human apoptosis-associated proteins inducing apoptosis, proteins containing amino acid sequences represented respectively by SEQ ID NOS:2, 4 and 6 are provided. Moreover, polynucleotides encoding these proteins, antibodies against these proteins, etc. are provided. These proteins, polynucleotides and antibodies are useful in, for example, diagnosing and treating cancer, autoimmune diseases, etc.
L'invention concerne des protéines, associées à l'apoptose humaine, induisant l'apoptose, dont les séquences en acides aminés sont respectivement représentées par les SEQ ID NOS: 2, 4 et 6. Elle concerne en outre des polynucléotides codant pour ces protéines, des anticorps contre ces protéines, et d'autres produits. Ces protéines, polynucléotides et anticorps sont utiles, par exemple, dans le diagnostic et le traitement du cancer, de maladies auto-immunes, et dans d'autres applications
Akiyama Nobutake
Kondoh Shinae
Akiyama Nobutake
Kondoh Shinae
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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