C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2156857
A human B-lymphoblastoid cell line which is identified as L612. The 1r612 cell line is an Epstein-Barr virus transformed cell line which secretes a human monoclonal antibody (L612) which is reactive with glycoconjugates having an epitope of terminal NeuAc~2-3 Galactose residue such as GM3 and GM4 present on a variety of human tumor tissues. The L612 ana'body is useful in treating patients with the epitope containing tumors and is also useful in raising anti-id antibodies for use as surrogate antigens and diagnostic reagents.
Smart & Biggar
The Regents Of The University Of California
LandOfFree
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