C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
150/13, 167/140,
C12N 15/38 (2006.01) A61K 39/245 (2006.01) C07K 14/03 (2006.01) C07K 16/08 (2006.01) C12N 7/00 (2006.01) C12N 7/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)
Patent
CA 1340403
A new human B-lymphotropic virus (HBLV) has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. A method for obtaining HBLV particles has the steps of growing a co-culture of infected patient blood with uninfected suitable target cells, isolating infected cells from the culture cell cloning, multiplying the infected cells by serial transmission, isolating a virus from the infected cell culture, and concentrating the virus. Various utilities of the new virus and products derived therefrom are described. Methods for detecting the presence of HBLV in a patient suffering from acquired immune deficiency syndrome; and for detecting antibodies specific to HBLV membrane antigens in human serum suspected of being infected with HBLV are also described.
543652
Gallo Robert C.
Salahuddin Syed Zaki
Borden Ladner Gervais Llp
Gallo Robert C.
Salahuddin Syed Zaki
U.s. Departm Ent Of Commerce The United States Of America Represented By The Secretary
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