Human b lymphotropic virus (hblv) isolation and products

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/38 (2006.01) A61K 39/245 (2006.01) C07K 14/03 (2006.01) C07K 16/08 (2006.01) C12N 7/00 (2006.01) C12N 7/02 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 1340403

A new human B-lymphotropic virus (HBLV) has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. A method for obtaining HBLV particles has the steps of growing a co-culture of infected patient blood with uninfected suitable target cells, isolating infected cells from the culture cell cloning, multiplying the infected cells by serial transmission, isolating a virus from the infected cell culture, and concentrating the virus. Various utilities of the new virus and products derived therefrom are described. Methods for detecting the presence of HBLV in a patient suffering from acquired immune deficiency syndrome; and for detecting antibodies specific to HBLV membrane antigens in human serum suspected of being infected with HBLV are also described.

543652

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