C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/26 (2006.01) C12N 5/10 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2629438
The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.
La présente invention concerne des anticorps se liant immunospécifiquement avec une affinité élevée au peptide B-natriurétique humain ou "BNP" (Brain Natriuretic Peptide), ou à l'un de ses fragments. L'invention concerne également des procédés de production et de sélection de ces anticorps, des immuno-essais du BNP humain ou de l'un au moins de ses fragments avec utilisation de ces anticorps, et enfin des compositions thérapeutiques contenant ces anticorps.
Brophy Susan E.
Pinkus Mary S.
Shih Jessie W.
Tieman Bryan C.
Tu Bailin
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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