Human calcium channel compositions and methods using them

Details Human calcium channel compositions and methods using them Human calcium channel compositions and methods using them

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/483 (2006.01) G01N 33/50 (2006.01) G01N 33/84 (2006.01)

Patent

CA 2166982

Isolated DNA encoding each of human calcium chanel .alpha.1-, .alpha.2-, .beta.- and .gamma.-subunits, including subunits that arise as splice variants of primary transcripts, is provided. In particular DNA clones encoding each of the .alpha.1A-1, .alpha.1A-2, .alpha.1E-1, .alpha.1C-2, .alpha.1E-3, .beta.3-1, .beta.2C, .beta.2D, .beta.2E and .beta.4 subunits of human calcium channels are provided. Cells and vectors containing the DNA, subunit specific antibodies and nucleic acid probes and methods for identifying that modulate the activity of human calcium channels are also provided.

L'invention porte sur de l'ADN isolé codant chacune des sous-unités alpha 1-, alpha 2-, beta - et gamma des canaux calciques humains, y compris pour des sous-unités apparaissant comme des variantes d'épissures de transcripts primaires, et en particulier sur des clones d'ADN codant chacune des sous-unités alpha 1A-1, alpha 1A-2, alpha 1E-1, alpha 1C-2, alpha 1E-3, beta 3-1, beta 2C, beta 2D, beta 2E, et beta 4 des canaux calciques humains. L'invention porte également sur des cellules et vecteurs contenant l'ADN, des anticorps spécifiques aux sous-unités, des sondes d'acide nucléique, et des méthodes d'identification des composés modulant l'activité des canaux calciques humains.

Affiliated with

Also associated with

Rating

Human calcium channel compositions and methods using them does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human calcium channel compositions and methods using them, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human calcium channel compositions and methods using them will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1824198