Human calcium transporter 1 gene, screening method of...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 1/21 (2006.01) C12N 5/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2512392

It is intended to provide a means which enables the genetic applications (insertion into an expression vector, transformation, etc.) of human CaT1 gene, the clarification of the calcium absorption activity mechanism (the presence of a factor affecting the regulation of the calcium absorption activity of human CaT1, etc.) and the confirmation and new finding of a calcium absorption regulator. Namely, human CaT1 gene, its plasmid vector, a transformant transformed by this plasmid vector, a method of screening a calcium absorption regulator and a screening kit therefor, and a calcium absorption promoter are provided.

L'objectif de la présente invention a été de trouver un moyen qui autorise les applications génétiques (insertion dans un vecteur d'expression, transformation, etc.) du gène CaT1 humain, la clarification du mécanisme d'action de l'absorption du calcium ( la présence d'un facteur affectant la régulation de l'activité d'absorption du calcium de CaT1 humain, etc.) et la confirmation et la nouvelle découverte d'un régulateur d'absorption du calcium. La présente invention concerne donc un gène CaT1 humain, son vecteur plasmidique, un transformant transformé par ce vecteur plasmidique, une méthode de criblage d'un régulateur d'absorption du calcium et une trousse de criblage correspondante ainsi qu'un promoteur d'absorption du calcium.

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