Human cancer inhibitory pentapeptide amides and esters

Details Human cancer inhibitory pentapeptide amides and esters Human cancer inhibitory pentapeptide amides and esters

C - Chemistry, Metallurgy

07

K

C07K 7/02 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2154206

The isolation, elucidation and synthetic replication of novel pentapeptide amides and esters are described. The compounds have the general structure Image in which R1 and R2 are selected as shown below: 12) R1 = -CH2-CH3 ; R2 = Image 14) R1 = -CH2-CH2 ; R2 = Image 16 a) R1 = CH3 ; R2 = -O-CH2CH2CH2CH2CH3 16 b) R1 = CH3 ; R2 = -O-CH2CH2CH2CH2CH2CH2CH2CH3 16 c) R1 = CH3 ; R2 = -NH-CH2CH2CH2CH2CH2CH3 28

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