Human casb12 polypeptide, a serine protease

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) A61K 31/70 (2006.01) A61K 38/48 (2006.01) C07K 16/40 (2006.01) C12N 7/01 (2006.01) C12N 9/64 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2323760

CASB12 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CASB12 polpypeptides and polynucleotides in diagnostics, and vaccines for prophylactic and therapeutic treatment of cancers, particulary ovarian and colon cancers, autoimmune diseases, and related conditions.

L'invention concerne des polypeptides et des polynucléotides CASB12, ainsi que des procédés de production desdits polypeptides CASB12 par des techniques de recombinaison. L'invention porte aussi sur des procédés d'utilisation des polypeptides et de polynucléotides CASB12 dans les diagnostics, et sur des vaccins pour le traitement prophylactique et thérapeutique de cancers, notamment des cancers des ovaires et du colon, des maladies auto-immunes et d'états associés.

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