Human cdnas encoding polypeptides having kinase functions

Details Human cdnas encoding polypeptides having kinase functions Human cdnas encoding polypeptides having kinase functions

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2305308

The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in phosphorylation reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, the use of such polypeptides in screening assays, and kits comprising these reagents.

La présente invention concerne des polypeptides humains isolés et purifiés à fonction kinase, les acides nucléiques codant ces polypeptides, des procédés de production de formes recombinées de ces polypeptides, des anticorps produits contre ces polypeptides, et des fragments de peptides obtenus à partir de ces polypeptides. Par ailleurs, cette invention concerne l'utilisation de ces polypeptides et des peptides fragmentés dans des réactions de phosphorylation et comme étalons de masse moléculaire, l'utilisation de ces polypeptides et des peptides fragmentés comme régulateurs de la fragmentation des peptides, l'utilisation de ces polypeptides dans des essais de dépistage, et enfin, des kits renfermant ces réactifs.

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