C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/28 (2006.01) A61K 31/00 (2006.01) C12N 9/08 (2006.01) G01N 33/573 (2006.01) G01N 33/576 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2443525
The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as potential targets for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitic C virus infections in an individual or in cells. Also mono- or polyclonal antibodies are disclosed effective for the treatment of HCV infections together with methods for treating Hepatitis C virus infections or for the regulation of Hepatitis C virus production wherein said antibodies may be used.
L'invention concerne une peroxydase-gastrointestinale de glutathione de protéine cellulaire humaine comme cibles potentielles pour une intervention médicale contre les infections dues au virus de l'hépatite C (HCV). De plus, la présente invention concerne un procédé de détection de composés servant dans la prophylaxie et/ou le traitement des infections dues au virus de l'hépatite C et un procédé de détection d'anticorps des infections dues au virus de l'hépatite C chez un individu ou dans des cellules. L'invention concerne également des anticorps monoclonaux ou polyclonaux efficaces dans le traitement des infections dues au virus de l'hépatite C ainsi que des procédés de traitement des infections dues au virus de l'hépatite C ou afin de réguler la production du virus de l'hépatite dans lesquels on peut utiliser lesdits anticorps.
Cotten Matthew
Herget Thomas
Obert Sabine
Axxima Pharmaceuticals Ag
Fetherstonhaugh & Co.
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