Human cgrp receptor binding proteins

Details Human cgrp receptor binding proteins Human cgrp receptor binding proteins

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) C07K 14/72 (2006.01)

Patent

CA 2746858

Antigen binding proteins that bind to human CGRP receptor (CGRP R) are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of CGRP R to CGRP, and are useful in a number of CGRP R related disorders, including the treatment and/or prevention of migraine headaches.

L'invention porte sur des protéines de liaison à un antigène qui se lient au récepteur CGRP humain (CGRP R). L'invention porte également sur des acides nucléiques codant pour la protéine de liaison à un antigène, sur des vecteurs et des cellules codant pour ceux-ci. Les protéines de liaison à un antigène peuvent inhiber la liaison de CGRP R à CGRP, et sont utiles dans un nombre de troubles liés à CGRP R, comprenant le traitement et/ou la prévention de maux de tête migraineux.

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