Human collagen processing and autoimplant use

Details Human collagen processing and autoimplant use Human collagen processing and autoimplant use

A - Human Necessities

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167/327, 167/103

A61K 38/39 (2006.01) A61L 27/00 (2006.01) A61L 27/24 (2006.01) C07K 14/78 (2006.01) C08H 1/06 (2006.01) A61F 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1336812

Production of a chemically modified, crosslinkable, telopeptide-containing, naturally crosslinked, solubilized collagen from tissue obtained from a sole human donor, for implanting in the same donor, by chemically modifying the tissue, e.g. by acylation and/or esterification, to form an autoimplantable, crosslinkable, telopeptide-containing, naturally crosslinked, collagen product, as a completely solubilized collagen solution, optionally of high index of refraction for correcting sight, or as a partially solubilized collagen suspension; and use of the product for altering the condition of in situ tissue of the same human donor by autoim- plantation, such as by crosslinking the product to form an implant device, by placing an effective amount of the product at the tissue site and crosslinking the product in situ, or by partially crosslinking the product and placing an effective amount thereof at the tissue site and optionally further crosslinking the product in situ.

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