C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) A61K 31/70 (2006.01) A61K 38/48 (2006.01) A61K 38/55 (2006.01) A61K 48/00 (2006.01) C07K 16/40 (2006.01) C12N 9/64 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2239260
Human KUZ polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human KUZ polypeptides and polynucleotides in the design of protocols for the treatment of inflammation, neural degeneration, allergic disorders, or other disorders involving a dis-regulation of the substrate cytokines or receptors, among others, and diagnostic assays for such conditions.
Divulgation de polypeptides et de polynucléotides homologues humains du gène KUZ, ainsi que de méthodes de production de tels polypeptides par des techniques de recombinaison. Des méthodes d'utilisation des polypeptides et des polynucléotides homologues humains du gène KUZ dans la conception de protocoles pour le traitement de l'inflammation, de la dégénérescence neuronale, des troubles allergiques ou d'autres troubles mettant en jeu un dérèglement des cytokines ou des récepteurs servant de substrats, entre autres, de même que des épreuves diagnostiques pour ces conditions sont également dévoilées.
Ellis Catherine Elizabeth
Jackson Jeffrey Richard
Mayer Ruth Judik
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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