Human ect2 and methods of use

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2425671

Human Ect2 popypeptide, fragments and derivatives, along with vectors and host cells for expression and production of Ect2 popypeptide are provided. Various methods of screening for agents that modulate interaction of Ect2 with an Ect2 binding agent, including high throughput methods, are also provided.

L'invention concerne un polypeptide Ect2 humain, des fragments et dérivés, ainsi que des vecteurs et cellules hôtes permettant l'expression et la production de polypeptide Ect2. L'invention traite également de diverses méthodes de criblage d'agents qui modulent l'interaction entre un Ect2 et un agent liant Ect2, notamment des méthodes à haut rendement.

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