Human epo mimetic hinge core mimetibodies, compositions,...

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) A61K 31/7088 (2006.01) A61P 3/08 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2648035

The present invention relates to at least one novel human EPO mimetic hinge core mimetibody or specified portion or variant, including isolated nucleic acids that encode at least one EPO mimetic hinge core mimetibody or specified portion or variant, EPO mimetic hinge core mimetibody or specified portion or variants, vectors, host cells, and methods of making and using thereof, for preventing or treating glucose intolerance and/or renal disease associated anemia, including therapeutic compositions, methods and devices.

La présente invention concerne au moins un nouveau mimétique de l'EPO humaine à région centrale à charnière ou un fragment ou variant spécifique, renfermant des acides nucléiques isolés codant pour au moins un mimétique de l'EPO à région centrale à charnière ou un fragment ou variant spécifié, un mimétique de l'EPO à région centrale à charnière ou des fragments ou variants spécifiés, des vecteurs, des cellules hôtes ainsi que des procédés de production et d'utilisation de ces derniers dans la prévention ou le traitement de l'intolérance au glucose et/ou de l'anémie associée à une néphropathie, y compris des dispositifs, des procédés et des compositions thérapeutiques.

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