Human glycosylation enzymes

Details Human glycosylation enzymes Human glycosylation enzymes

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/43 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 9/88 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2361593

The present invention relates to novel human glycosylation enzyme polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human glycosylation enzyme polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human glycosylation enzyme polypeptides.

La présente invention concerne de nouveaux polypeptides enzymatiques de glycosylation humains, ainsi que des acides nucléiques isolés contenant les régions codantes des gènes codant pour ces polypeptides. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des techniques de recombinaison permettant de produire lesdits polypeptides enzymatiques humains de glycosylation. L'invention concerne enfin des méthodes diagnostiques et thérapeutiques utilisées pour le diagnostic et le traitement des troubles liés à ces nouveaux polypeptides enzymatiques de glycosylation humains.

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