Human gp130 protein

C - Chemistry – Metallurgy – 12 – N

Patent

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530/13, 195/1.23

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2022610

Human gp130 protein having at least the following properties: (1) the protein has an affinity with a complex of IL-6 (interleukin-6) and an IL-6 receptor (interleukin-6 receptor); (2) the protein shows an apparent molecular weight of 130 kDa in SDS-polyacrylamide electrophoresis; and (3) the protein participates in the transmission of IL-6 signal; DNA coding for the protein, an expression plamid containing the DNA; and a process for production of the protein using the expression plasmid.

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