Human granulocyte-macrophage colony stimulating factor and...

C - Chemistry – Metallurgy – 12 – N

Patent

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195/1.14, 195/1.

C12N 15/85 (2006.01) C07K 14/535 (2006.01) C12N 15/27 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1335717

An expression vector for the production of human granulocyte-macrophage colony stimulating factor (hGM-CSF) in a mammalian cell host is provided, the expression vector comprising in sequence: an SV40 origin of DNA replication; an SV40 early region promoter; an SR.alpha. promoter; a splice junction and a nucleotide sequence capable of encoding human granulocyte- macrophage colony stimulating factor; and a polyadenylation site.

572029

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