Human growth hormone crystals and methods for preparing them

Details Human growth hormone crystals and methods for preparing them Human growth hormone crystals and methods for preparing them

A - Human Necessities

61

K

A61K 38/27 (2006.01) C07K 14/61 (2006.01)

Patent

CA 2512052

The present invention relates to stable, extended release crystals of human growth hormone or a human growth hormone derivative and compositions or formulations comprising such crystals. The invention further provides methods for producing those crystals and compositions. The invention further provides methods for treatment of an individual having disorders associated with human growth hormone deficiency or which are ameliorated by treatment with human growth hormone using those crystals and compositions or formulations.

La présente invention concerne des cristaux stables à libération prolongée d'une hormone de croissance humaine ou d'un dérivé d'hormone de croissance humaine, ainsi que des compositions ou des préparations comprenant ces cristaux. L'invention concerne également des procédés de production de ces cristaux et de ces compositions. Elle se rapporte en outre à des méthodes de traitement d'un individu présentant des troubles associés à une carence en hormone de croissance humaine ou combattus par traitement avec une hormone de croissance humaine au moyen de ces cristaux et de ces compositions ou préparations.

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