Human h37 proteins and cdnas encoding the same

Details Human h37 proteins and cdnas encoding the same Human h37 proteins and cdnas encoding the same

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2348732

This application provides human H37 protein having an amino acid sequence of SEQ ID NO: 1 or NO: 2; human gene encoding the protein; cDNA of the human gene which has a base sequence of SEQ ID NO: 3 or NO: 4; DNA fragment comprising a partial sequence of the cDNA; recombinant vector having the cDNA; antibody against human H37 protein; and a method for controlling the proliferation of cells by introducing the above DNA or antibody into the cells.

L'invention concerne des protéines humaines H37 possédant la séquence d'acides aminés représentée par SEQ ID NO:1 ou 2, des gènes humains codant pour ces protéines, des ADNc de ces gènes possédant la séquence de base représentée par SEQ ID NO:3 ou 4, des fragments d'ADN comprenant une partie des séquences de ces ADNc, des vecteurs recombinants possédant ces ADNc, un anticorps dirigé contre la protéine humaine H37, ainsi qu'un procédé de régulation de la prolifération cellulaire, consistant à transférer les ADN ou anticorps ci-dessus, dans ces cellules.

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