C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G06F 17/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2368590
The invention provides isolated nucleic acid and amino acid sequences of hHAC3, antibodies to hHac3, methods of detecting hHAC3, and methods of screening for modulators hyperpolarization-activated ration channels using biologically active hHAC3. The invention further provides, in a computer system, a method of screening for mutations of human HAC3 genes as well as a method for identifying a three-dimensional structure of human HAC3 polypeptides.
L'invention concerne des séquences isolées d'acides nucléiques et d'acides aminés de hHAC3, des anticorps à hHAC3, des procédés de détection de hHAC3 et des procédés pour cribler au moyen de hHAC3 biologiquement actifs les canaux cationiques activés à la recherche des modulateurs activés par hyperpolarisation. L'invention concerne en outre, dans un système informatique, un procédé de criblage des gènes humains HAC3 à la recherche des mutations ainsi qu'un procédé d'identification d'une structure tridimensionnelle de polypeptides HAC3 humains.
Fetherstonhaugh & Co.
Icagen Inc.
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