Human homologue of unc-53 protein of c. elegans

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2330179

There is disclosed human homologues of the UNC-53 protein of C. elegans and cDNA sequences coding for said homologues or functional equivalents thereof. The invention also relates to processes for identifying compounds which control cell behaviour, compounds identified and pharmaceutical compositions containing them in addition to processes and assays for identifying disease states in which said gene or protein is dysfunctional.

L'invention concerne des homologues humains de la protéine UNC-53 de C. elegans et un codage de séquences d'ADN de ces homologues ou de leurs équivalents fonctionnels. L'invention concerne également des procédés d'identification de composés régulant le comportement cellulaire, de composés identifiés et de compositions pharmaceutiques les contenant, ainsi que des procédés et dosages d'identification d'états pathologiques dans lesquels ce gène ou cette protéine présente un dysfonctionnement.

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