Human hyperpolarization-activated cyclic nucleotide-gated...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2432274

The present invention is directed to novel human DNA sequences encoding human HCN3 proteins, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and activators of cation channels containing the human HCN3 proteins.

La présente invention concerne de nouvelles séquences d'ADN chez l'homme codant les protéines HCN3 de l'homme, la protéine codée par les séquences d'ADN, les vecteurs comprenant les séquences d'ADN et les cellules hôtes contenant ces vecteurs. L'invention traite de procédés permettant d'identifier des inhibiteurs et des activateurs de canaux cationiques contenant ces protéines HCN3 de l'homme.

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