Human hyperpolarization-activated cyclic nucleotide-gated...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2435292

The present invention is directed to novel human DNA sequences encoding human HCN1 proteins, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and activators of cation channels containing the human HCN1 proteins.

La présente invention concerne des séquences d'ADN humain codant des protéines HCN1 humaines, la protéine codée par les séquences d'ADN, des vecteurs renfermant lesdites séquences d'ADN, des cellules hôtes contenant ces vecteurs, et les méthodes d'identification des inhibiteurs et activateurs des canaux cationiques renfermant les protéines HCN1 humaines.

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