Human il-1 epsilon dna and polypeptides

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/25 (2006.01) A61K 38/20 (2006.01) A61P 29/00 (2006.01) A61P 37/04 (2006.01) C07K 14/545 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2340790

The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.

L'invention concerne de nouveaux polypeptides humains purifiés isolés IL-1 epsilon, les acides nucléiques codant pour ces polypeptides, des procédés de production des formes de recombinaison de ces polypeptides, des anticorps produits contre ces polypeptides, et des peptides fragmentés dérivés de ces polypeptides. L'invention concerne également l'utilisation des ces polypeptides et des peptides fragmentés dans des réactions cellulaires et immunitaires, et comme marqueurs de poids moléculaire. L'invention concerne, en outre, l'utilisation de ces polypeptides et des peptides fragmentés comme commandes de fragmentation de peptide ainsi que des kits comprenant ces réactifs.

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