Human insulin analogues

Details Human insulin analogues Human insulin analogues

C - Chemistry, Metallurgy

12

N

195/1.32, 530/7.

C12N 15/17 (2006.01) A61K 38/28 (2006.01) C07K 14/62 (2006.01) C12P 21/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2006578

1989-12-06, ATS/KGF 3343.010-DK Abstract Human insulin analogues having a positively charged amino acid residue, i.e. Lys or Arg, in position B28, i.e. in posi- tion 8 in the B-chain calculated from [GlyB20], and optional- ly being further modified in the C-terminal end of the B- chain from [PheB24] to the C-terminal amino acid residue and optionally A21 and/or B3 being different from Asn as well as insulin preparations containing the human insulin analogues are provided.

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