Human interferon-gamma (infgamma) variants

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/23 (2006.01) A61K 38/21 (2006.01) C07K 14/57 (2006.01)

Patent

CA 2644127

The present invention relates to human interferon-gamma variants with improved thermostability, to a nucleic acid encoding said variants, to a pharmaceutical composition containing them, and to their use for the treatment of a viral infection and of cancer.

La présente invention concerne des variants de l'interféron gamma humain présentant une thermostabilité améliorée, un acide nucléique codant pour celles-ci, une composition pharmaceutique les comprenant, ainsi que leur utilisation pour le traitement d'infection virale, et de cancer.

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