C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/715 (2006.01) A61K 38/20 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2155629
A previously undescribed Interleukin-6 inhibitor activity has been successfully isolated from the supernatant of the human promyelocytic leukemia cell line HL-60. Treatment of the HL-60 cell line with cycloheximide prevents the appearance of the inhibitory activity in the cellular supernatant. Incubation of the HL-60 supernatant with trypsin destroys the activity. The above observations indicate the inhibitor is a protein. Membrane and gel filtration studies indicate the protein has a molecular weight between 10,000 and 30,000 daltons. The inhibitor was partially isolated from other proteins by dye-ligand and reverse phase chromatography.
Corporation Bayer
Faris Susan K.
Lembach Kenneth J.
Penza Delia E.
Corporation Bayer
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Human interleukin 6 inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Human interleukin 6 inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human interleukin 6 inhibitor will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1823805