Human inwardly rectifying potassium channel subunit

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 1/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C12N 5/00 (2006.01) C12P 1/00 (2006.01) C12P 21/04 (2006.01) C12P 21/06 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2386236

The present invention is directed to novel human DNA sequences encoding Kir5.1, a potassium channel subunit, the protein encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of potassium channels containing the human Kir5.1 subunit.

La présente invention concerne des séquences d'ADN humain codantes pour Kir5.1, une sous-unité de canal potassique, la protéine codée par ces séquences d'ADN, des vecteurs comprenant ces séquences d'ADN, des cellules hôtes contenant ces vecteurs et des techniques d'identification d'inhibiteurs et d'antagonistes des canaux potassiques contenant la protéine humaine Kir5.

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