C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2365440
The present invention provides a novel family of human ion channel proteins (ICPs). The invention additionally provides for agonists, antagonists, antibodies, antisense molecules that are specific for the ICPs, and further provides genetically engineered expression vectors for the ICPs and host cells comprising the same. The invention further provides for processes for identifying/producing molecules that effect ICP activity that comprise the use of the disclosed ICPs or genes encoding the same.
L'invention concerne une nouvelle famille de protéines de canal ionique (ICPs) chez l'homme. L'invention traite également d'agonistes, d'antagonistes, d'anticorps, de molécules antisens qui sont spécifiques à ces protéines et a aussi pour objet des vecteurs d'expression génétiquement modifiés pour ces protéines et des cellules hôtes contenant ces derniers. L'invention concerne également des procédés permettant d'identifier/de produire des molécules qui assurent l'activité de ces protéines et qui consistent à utiliser ces protéines ou des gènes codant ces dernières.
Friedrich Glenn A.
Olson Andrew
Sands Arthur T.
Turner Alexander C. Jr.
Zambrowicz Brian
Lexicon Genetics Incorporated
Osler Hoskin & Harcourt Llp
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