C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 38/45 (2006.01) C12N 9/12 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2311610
The present invention relates to a novel IRAK-2 protein which is a member of the IL-1 signaling pathway. In particular, isolated nucleic acid molecules are provided encoding the human IRAK-2 protein. IRAK-2 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic methods for detecting IRAK-2 related disorders and therapeutic methods for treating IRAK-2 related disorders.
La présente invention concerne une nouvelle protéine IRAK-2, membre de la voie de signalisation de l'IL-1. En particulier, l'invention concerne des molécules d'acide nucléique isolées codant la protéine IRAK-2 humaine. L'invention concerne également des polypeptides IRAK-2, ainsi que des vecteurs, des cellules hôtes et des méthodes de recombinaison permettant de les produire. L'invention concerne, en outre, des méthodes diagnostiques permettant de détecter des troubles liés à l'IRAK-2 et des méthodes thérapeutiques permettant de traiter des troubles liés à l'IRAK-2.
Dixit Vishva M.
Feng Ping
Muzio Marta
Ni Jian
Human Genome Sciences Inc.
Mbm Intellectual Property Law Llp
The Regents Of The University Of Michigan
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