Human leukemia virus-related peptides, antibodies of the...

Details Human leukemia virus-related peptides, antibodies of the... Human leukemia virus-related peptides, antibodies of the...

C - Chemistry, Metallurgy

07

K

167/140, 530/7.0

C07K 7/06 (2006.01) A61K 39/395 (2006.01) C07K 7/08 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01)

Patent

CA 1262014

ABSTRACT OF THE DISCLOSURE An antibody of a human leukemia virus-related pep- tide obtained by collecting an antibody produced in a mammal body by administering to the mammal an antigen prepared by reacting a human leukemia virus-related peptide selected from the group consisting of: (a) a peptide represented by formula (1): H-Tyr-Val-Glu-Pro-Thr-Ala-Pro-Gln-Val-Leu-H (1) (b) a peptide represented by formula (2): R-Ile-Pro-His-Pro-Lys-Asn-Ser-Ile-Gly-Gly-Glu-Val-OH (2) wherein R is the same as defined above; (c) a peptide represented by formula (3): R-Thr-Trp-Thr-Pro-Lys-Asp-Lys-Thr-Lys-Val-Leu-OH (3) wnerein R is the same as defined above; (d) a peptide represented by formula (4): H-Val-Val-Gln-Pro-Lys-Lys-Pro-Pro-Pro-Tyr-OH (4) (e) a peptide represented by formula (5): R-Met-Gly-Gln-Ile-Phe-Ser-Arg-Ser-Ala-Ser-Pro-OH (5) wherein R is the same as defined above; and (f) a peptide represented by formula (6): H-Tyr-Pro-Glu-Gly-Thr-Pro-Lys-Asp-Pro-Ile-Leu-Arg-Ser-Leu-OH (6) as a hapten, with a carrier in the presence of a hapten- carrier binding agent.

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