Human lymphotoxin

Details Human lymphotoxin Human lymphotoxin

C - Chemistry, Metallurgy

12

P

167/129

C12P 21/00 (2006.01) C07K 14/525 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1241597

HUMAN LYMPHOTOXIN AND DERIVATIVES THEREOF, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT Abstract Human lymphotoxin is prepared substantially free of impurities by a process which comprises (a) obtaining an extract, supernatant or filtrate from a cell culture which produces lymphotoxin; (b) treating said extract, supernatant, or filtrate with a lentil lectin absorbant; (c) selectively eluting the lymphotoxin from the absorbant. The lymphotoxin or salts or derivatives thereof can be used in a pharmaceutical composition, e.g. for treating tumors.

433066

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