Human mena isoforms serve as markers of epithelial to...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2737141

The present invention discloses a method for discriminating between sensitive and resistant tumours to a treatment with EGFR inhibitor drugs comprising: in vitro testing whether tumour material expresses the hMena+11a splicing variant of hMe-na, the tumour positive to said testing being sensitive to the treatment.

La présente invention concerne un procédé destiné à différencier des tumeurs résistantes de tumeurs sensibles à un traitement avec des médicaments inhibiteurs de lEGFR, consistant à : tester in vitro si la matière tumorale exprime la variante d'épissage de hMena, une tumeur positive audit test étant sensible au traitement.

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