Human metabotropic glutamate receptor

Details Human metabotropic glutamate receptor Human metabotropic glutamate receptor

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/85 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2246751

A human metabotropic glutamate receptor (mGluR) protein is identified, sequenced, and cloned. The receptor may be used to screen for compounds that modulate the activity of the mGluR. The recombinant mGluR as well as compounds that modulate mGluR activity may be used in the diagnosis and treatment of neurological disorders and diseases.

On a identifié, séquencé et cloné une nouvelle protéine réceptrice humaine du glutamate métabotrope (mGluR). On peut utiliser ce récepteur pour cribler des composés qui modulent l'activité de la protéine mGluR. On peut également utiliser la protéine mGluR recombinée, de même que des composés qui modulent l'activité de mGluR, dans le diagnostic et le traitement des troubles et maladies neurologiques.

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