Human minor vault protein p193

Details Human minor vault protein p193 Human minor vault protein p193

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2330833

Purified human minor vault protein p193 or purified biologically active variants thereof, or a combination of purified human minor vault protein p193 and biologically active variants thereof are disclosed. A polynucleotide molecule encoding human minor vault protein p193, or the complementary DNA is also disclosed. Furthermore, a method of diagnosing and a method of treating patients with multidrug resistant cancer is provided.

Cette invention concerne une protéine voûte mineure humaine p193 purifiée, des variantes biologiquement actives et purifiées de cette protéine, ainsi qu'une combinaison de cette protéine voûte mineure humaine p193 purifiée et de ses variantes biologiquement actives et purifiées. Cette invention concerne également une molécule de polynucléotide qui code la protéine voûte mineure humaine p193, ou l'ADN complémentaire. Cette invention concerne en outre un procédé de diagnostic et un procédé de traitement destinés à des patient qui souffrent d'un cancer résistant à de multiples médicaments.

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