Human monoclonal antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 31/14 (2006.01) C07H 21/00 (2006.01) C07K 16/10 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2270288

This invention relates to novel human monoclonal antibodies (mAbs) and to the genes encoding same. More specifically, this invention relates to human monoclonal antibodies specifically reactive with an epitope of the fusion (F) protein of Respiratory Syncytial Virus (RSV). Such antibodies are useful for the therapeutic and/or prophylactic treatment of RSV infection in human patients, particularly infants and young children.

L'invention se rapporte à de nouveaux anticorps monoclonaux humains (mAbs) et aux gènes codant pour lesdits mAbs. Plus particulièrement, l'invention concerne des anticorps monoclonaux humains qui réagissent spécifiquement avec un épitope de la protéine de fusion (F) du virus respiratoire syncytial (VRS). Ces anticorps peuvent être utilisés dans le traitement thérapeutique et/ou prophylactique des patients infectés par le VRS, en particulier des nourrissons et de jeunes enfants.

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