Human monoclonal antibodies against rabies viruses, the...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/10 (2006.01) A61K 39/205 (2006.01) A61K 39/42 (2006.01) C07K 14/145 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2037446

- 1 - BEHRINGWERKE AKTIENGESELLSCHAFT HOE 90/B 010 - Ma 809 Dr. Lp/rd Abstract Human monoclonal antibodies against rabies viruses, the production and the use thereof The present patent application relates to human mono- clonal antibodies against rabies viruses, and the use thereof in diagnosis, prevention and therapy. Antibodies against the epitope, defined by the human monoclonal antibody TW-1, on the 67 kD glycoprotein of the virus envelope gives a better protection against the outbreak of rabies, after infection has taken place, than commer- cial preparations of human immunoglobulins.

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