Human monoclonal antibodies and lymphokines

Details Human monoclonal antibodies and lymphokines Human monoclonal antibodies and lymphokines

C - Chemistry, Metallurgy

12

N

167/37, 195/71,

C12N 5/02 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C07K 16/30 (2006.01) C12N 5/16 (2006.01)

Patent

CA 1200484

Human Monoclonal Antibodies and Lymphokines Abstract A method is described for separating fused cells, resulting from fusion of human cells known to produce a specific antibody or a specific lymphokine with malignant human partner cells, from the said partner cells which comprises addition of specific antiserum capable of identifying antigenic specificities unique to the clone and non-reactive with the non-fused partner cells. After reaction of the fused cell with the antiserum, the reaction product is separated within 24 hours by indirect rosetting.

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