Human monoclonal antibodies having reactivity with...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/40 (2006.01) C07K 16/12 (2006.01) C12N 5/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2028815

- 85 - ABSTRACT OF THE DISCLOSURE Human-human hybridomas of the present invention can secrete, in large quantities in serum-free media, monoclonal antibodies which are capable of reacting with at least one of the serotype, disease-causing bacteria of Pseudomonas aeruginosa. Various combinations of the human monoclonal antibodies provide potent preparations for prophylaxis and treatment of Pseudomonas aeruginosa infectious diseases.

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