C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.105
C12N 5/28 (2006.01) C07K 16/10 (2006.01) C12N 15/08 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1339858
Human monoclonal antibodies which belong to the IgG1 subclass and which are specific for HIV gp41 and gp120, along with the hybridomas producing them, are described. Also described is a method for producing human monoclonal antibodies which does not involve transformation by Epstein-Barr virus. These hybridomas are formed by fusing mouse myeloma cells and lymphocytes from the lymph nodes of HIV-seropositive donors. The monoclonal antibodies produced by HB 9669 and HB 9670 are predicted to be useful in the diagnostic, prevention and therapy of HIV infection.
588825
Hersh Evan
Lake Douglas
Masuho Yasuhiko
Matsumoto Yoh-Ichi
Petersen Eskild
Goudreau Gage Dubuc
Hersh Evan
Lake Douglas
Masuho Yasuhiko
Matsumoto Yoh-Ichi
LandOfFree
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