Human monoclonal antibodies to influenza m2 protein and...

Details Human monoclonal antibodies to influenza m2 protein and... Human monoclonal antibodies to influenza m2 protein and...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/42 (2006.01) A61P 31/16 (2006.01) C07K 16/10 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 5/18 (2006.01) C12P 21/08 (2006.01) C07K 14/11 (2006.01)

Patent

CA 2585104

Human, humanized and chimeric monoclonal antibodies that bind to influenza M2 protein. A human monoclonal antibody that binds to influenza M2 protein having different amino acid sequences. The antibodies are useful for, among other things, treatment, diagnostics, purifying and isolating M2 or influenza virus, and identifying the presence of M2 or influenza virus in a sample or a subject.

L'invention concerne des anticorps monoclonaux humains, humanisés ou chimères, qui se lient à la protéine M2 de la grippe; et un anticorps monoclonal humain qui se lie à la protéine M2 de la grippe présentant différentes séquences d'acides aminés. Les anticorps de l'invention sont utiles, entre autres, pour traiter, diagnostiquer, purifier et isoler la protéine M2 ou le virus de la grippe, et pour identifier la présence de la protéine M2 ou du virus de la grippe dans un prélèvement ou chez un sujet.

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