C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) C12N 15/63 (2006.01) G01N 33/576 (2006.01)
Patent
CA 2474801
The invention refers to a human antibody, or its functional fragments, directed against the HCV E2 glycoprotein, able to have a neutralizing activity in vivo; a composition for anti-HCV therapy comprising in a therapeutically effective amount the antibody; a composition for topical use in gel, creme, ointment and ovule formulations; the use of the antibody for validating anti- HCV vaccines.
La présente invention concerne un anticorps humain, ou ses fragments fonctionnels, dirigés contre la glycoprotéine VHC/E2, capable d'avoir un effet d'activité de neutralisation in vivo ; une composition pour la thérapie anti-VHC comprenant en quantité thérapeutiquement efficace ledit anticorps ; une composition d'usage topique sous forme de gel, de crème, d'onguent et de comprimé vaginal ; l'utilisation dudit anticorps pour la validation de vaccin anti-VCH.
Burioni Roberto
Dennison Associates
General Antibodies And Biotechnologies S.r.l. (ga S.r.l.)
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