C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01) C12N 5/20 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2631015
The invention provides antibodies that specifically bind to OX40 (CD 134), referred to as OX40 antibodies, anti-OX40 or anti-OX40 antibodies. Invention antibodies that specifically bind to OX40 include mammalian (human, primate, etc.), humanized and chimeric anti-OX40 antibodies. Invention antibodies and antibody subsequences (fragments) that specifically bind to OX40 include purified and isolated antibodies, as well as pharmaceutical formulations thereof, are useful in various methods including treatment, screening and detection methods.
L'invention concerne des anticorps qui se lient spécifiquement à OX40 (CD 134), appelés anticorps OX40, anti-OX40 ou anticorps anti-OX40. Ces anticorps, qui se lient spécifiquement à OX40, comprennent des anticorps anti-OX40 de mammifère (humain, primate, etc.), humanisés et chimères. Les anticorps de l'invention et les sous-séquences d'anticorps (fragments) se liant spécifiquement à OX40 comprennent des anticorps purifiés et isolés ainsi que des formulations pharmaceutiques de ceux-ci, et sont utiles dans divers procédés, y compris des procédés de traitement, de criblage et de détection.
Croft Michael
Kato Shinichiro
Soloff Nugent Rachel
Yoshida Hitoshi
Kirin Pharma Kabushiki Kaisha
La Jolla Institute For Allergy And Immunology
Smart & Biggar
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