Human monoclonal antibody specifically binding to surface...

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/08 (2006.01) A61K 9/127 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/30 (2006.01) C12N 5/28 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072249

The present invention is directed to a human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti- cancer agent or toxin is also provided.

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