Human nerve growth factor exon 1 and exon 3 promoters

Details Human nerve growth factor exon 1 and exon 3 promoters Human nerve growth factor exon 1 and exon 3 promoters

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A01K 67/00 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/48 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2280211

Novel human nerve growth factor exon 1 promoter, human nerve growth factor exon 3 promoter, fragments thereof, and modified forms thereof are described. The invention is also directed to vectors containing such promoters, cells transformed with the same, including animal models and transgenic animals containing such sequence and assay methods using these promoters.

L'invention concerne un nouveau promoteur de l'exon 1 du facteur humain de croissance du tissu nerveux, un promoteur de l'exon 3 de ce facteur, des fragments de ce promoteur ainsi que des formes modifiées de celui-ci. L'invention concerne également des vecteurs contenant de tels promoteurs, des cellules transformées à l'aide de ceux-ci, notamment des modèles animaux et des animaux transgéniques contenant une telle séquence, ainsi que des procédés de dosage effectués au moyen de ces promoteurs.

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